diff --git a/plinth/modules/matrixsynapse/__init__.py b/plinth/modules/matrixsynapse/__init__.py
index 606f6f47d..46ed62539 100644
--- a/plinth/modules/matrixsynapse/__init__.py
+++ b/plinth/modules/matrixsynapse/__init__.py
@@ -126,6 +126,11 @@ class MatrixSynapseApp(app_module.App):
         config = self.get_component('turn-matrixsynapse').get_configuration()
         update_turn_configuration(config, force=True)
 
+    def uninstall(self):
+        """De-configure and uninstall the app."""
+        super().uninstall()
+        privileged.uninstall()
+
 
 class MatrixSynapseTurnConsumer(TurnConsumer):
     """Component to manage Coturn configuration for Matrix Synapse."""
diff --git a/plinth/modules/matrixsynapse/privileged.py b/plinth/modules/matrixsynapse/privileged.py
index 8aa6fa2a7..f5b48459d 100644
--- a/plinth/modules/matrixsynapse/privileged.py
+++ b/plinth/modules/matrixsynapse/privileged.py
@@ -339,3 +339,10 @@ def _generate_mac(shared_secret: str, nonce: str, user: str, password: str,
         mac.update(user_type.encode('utf8'))
 
     return mac.hexdigest()
+
+
+@privileged
+def uninstall():
+    """Delete configuration and data directories."""
+    for item in ['/etc/matrix-synapse/conf.d', '/var/lib/matrix-synapse']:
+        shutil.rmtree(item, ignore_errors=True)
diff --git a/plinth/modules/matrixsynapse/tests/test_functional.py b/plinth/modules/matrixsynapse/tests/test_functional.py
index 4d844fefd..9a57103fd 100644
--- a/plinth/modules/matrixsynapse/tests/test_functional.py
+++ b/plinth/modules/matrixsynapse/tests/test_functional.py
@@ -24,3 +24,9 @@ class TestMatrixSynapseApp(functional.BaseAppTests):
         functional.install(session_browser, self.app_name)
         functional.app_select_domain_name(session_browser, self.app_name,
                                           'mydomain.example')
+
+    def test_uninstall(self, session_browser):
+        """After uninstall test, after installing select the domain again."""
+        super().test_uninstall(session_browser)
+        functional.app_select_domain_name(session_browser, self.app_name,
+                                          'mydomain.example')